Biosafety levels (1 through 4) have been established to provide standardized safety protocols for biological research in professional settings, to protect researchers and the general public. While the new biohacker might only need a reduce set of lab safety standards (here called biosafety level 0), any bio-researcher needs an awareness of biosafety levels as they develop into commercial (level 1) or medical (level 2) research. Biosafety levels 3 and 4 will be discussed for completeness and to impress on the home researcher the difficulty in safely working with virulent pathogens.